Title:
Meta analysis of clinical trials of nut consumption

Summary:
We propose to conduct a formal meta-analysis of all clinical trials conducted to date on the cholesterol-lowering effects of nuts. These included 11 published trials and approximately six trials that have been completed but are awaiting publication. The study will have the following two goals:

  • Provide a precise and accurate unified estimate of the effect of nuts on serum cholesterol levels.
  • Formally test the hypothesis that the cholesterol-lowering effect of nuts is greater than that of their constituent fatty acids.

Publications:
Sabaté J, Oda K, Ros E. Nut consumption and blood lipids: A pooled analysis of 25 intervention trials. Arch Int Med 2009 (in press).

Presentations:
Tanzman JS, Sabaté J. Do non-fat constituents contribute to the cholesterol-lowering effect of nuts? A meta-analysis. Experimental Biology 2004, Washington, DC, April 2004. View abstract

Sabaté J., Fulgoni V. Nut consumption lowers total and LDL-cholesterol but does not change HDL-cholesterol serum levels: results of a pool analysis. Ninth European Nutrition Congress, Rome, Italy, October 2003. View abstract

Sabaté J, Wien M, Hasso-Haddad E. Impact of nut intake on serum lipids and lipoproteins: a pooled analysis of 25 intervention trials. 19th International Congress on Nutrition, Bangkok, Thailand, October 2009. View abstract

Date: 2004

Funded by: The International Treenut Council