Effect of almonds on antioxidant status and platelet activity

The objective of this study was to assess the dose response effect of almond intake on plasma and red blood cell tocopherol concentrations in healthy adults enrolled in a randomized, crossover feeding trial. Participants were 16 healthy men and women, aged 41±13 years. After a 2-week run-in period, participants were fed three diets for 4 weeks each: a control diet, a low-almond diet, and a high-almond diet, in which almonds contributed 0%, 10%, and 20% of total energy, respectively. Changes in blood tocopherol levels were assayed by high pressure liquid chromatography. Incorporating almonds into the diet helped meet the revised Recommended Dietary Allowance of 15 mg/day α-tocopherol and increased lipid adjusted plasma and red blood cell α-tocopherol concentrations. A significant dose-response effect was observed between percent energy in the diet from almonds and plasma ratio of α-tocopherol to total cholesterol.

Jambazian PR, Haddad E, Rajaram S, Tanzman J, Sabaté J. Almonds in a diet simultaneously improve plasma alpha-tocopherol concentrations and reduce plasma lipids. J Am Diet Assoc, 2005;105:449-454. full text

Jambazian P, Haddad E, Tanzman J, Sabaté J. Incorporating almonds in diet improves plasma alpha tocopherol levels. Experimental Biology ‘01. Orlando, FL, April 2001. abstract

Date: 2000

Funded by: Almond Board of California